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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Recent Progress in the Synthesis and Applications of Heterocycles Derived from Enaminonitriles

Author(s): Samir Bondock, Abd El-Gaber Tarhoni and Ahmed A. Fadda

Volume 15, Issue 5, 2011

Page: [753 - 781] Pages: 29

DOI: 10.2174/138527211794519041

Price: $65

Abstract

Recent progress in the synthesis and use of enaminonitriles as precursors for carbocyclic and heterocyclic compounds is reviewed. The synthetic routes for preparation of enaminonitriles are based on addition and condensation reactions. Enaminonitriles can be used as building blocks for carbocyclic, five, six, and seven-membered heterocycles as well as fused heterocyclic compounds. Biological and industrial applications of heterocycles derived from enaminonitriles are also discussed.

Keywords: Enaminonitriles, Synthesis, Dimethylformamide-dimethylacetal, N-nucleophiles, C-nucleophiles, Heterocycles


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