Abstract
The combination of diabetes mellitus and coronary artery disease (CAD) constitutes an aggressive disease characterized biologically by chronic inflammatory, proliferative and pro-thrombotic situation. In the “diabetic patient” the increased frequency and gravity of simultaneous myocardial infarction and the deterioration of congestive heart failure contribute to the inevitable unfavourable final result. Diabetes accelerates the natural course of atherosclerosis and involves a great number of coronary vessels with more diffuse atherosclerotic lesions. Moreover, the risks of plaque ulceration and thrombosis have been shown to be considerably higher in diabetic patients. The treatment should be also aggressive and be based on the combined treatment of CAD and the effective regulation of glucose levels. The decision of revascularization in the diabetic patient should be posed relatively earlier. The surgical choice of revascularization seems to be advantageous over the interventional, with better early and late results.
Keywords: Coronary artery disease, Diabetes mellitus, Coronary artery bypass grafting, Percutaneous transluminal coronary angioplasty, Myocardial infarction, Revascularization, percutaneous transluminal, Surgical revascularization, prothrombotic situation, lipoproteins, manifestations, triglyceride-rich, triggering mechanisms, Plaque-angiogenesis, catabolism, CABG surgery, Abciximab, ischemia, SPECT, AWESOME, worsening symptoms, BASKET-LATE, MACE, perioperatively
Current Diabetes Reviews
Title: Surgical or Interventional Revascularization in Diabetic Patients with Coronary Artery Disease?
Volume: 6 Issue: 6
Author(s): E. Apostolakis, I. Koniari, D. Velissaris and Efstratios N. Koletsis
Affiliation:
Keywords: Coronary artery disease, Diabetes mellitus, Coronary artery bypass grafting, Percutaneous transluminal coronary angioplasty, Myocardial infarction, Revascularization, percutaneous transluminal, Surgical revascularization, prothrombotic situation, lipoproteins, manifestations, triglyceride-rich, triggering mechanisms, Plaque-angiogenesis, catabolism, CABG surgery, Abciximab, ischemia, SPECT, AWESOME, worsening symptoms, BASKET-LATE, MACE, perioperatively
Abstract: The combination of diabetes mellitus and coronary artery disease (CAD) constitutes an aggressive disease characterized biologically by chronic inflammatory, proliferative and pro-thrombotic situation. In the “diabetic patient” the increased frequency and gravity of simultaneous myocardial infarction and the deterioration of congestive heart failure contribute to the inevitable unfavourable final result. Diabetes accelerates the natural course of atherosclerosis and involves a great number of coronary vessels with more diffuse atherosclerotic lesions. Moreover, the risks of plaque ulceration and thrombosis have been shown to be considerably higher in diabetic patients. The treatment should be also aggressive and be based on the combined treatment of CAD and the effective regulation of glucose levels. The decision of revascularization in the diabetic patient should be posed relatively earlier. The surgical choice of revascularization seems to be advantageous over the interventional, with better early and late results.
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Cite this article as:
Apostolakis E., Koniari I., Velissaris D. and N. Koletsis Efstratios, Surgical or Interventional Revascularization in Diabetic Patients with Coronary Artery Disease?, Current Diabetes Reviews 2010; 6 (6) . https://dx.doi.org/10.2174/157339910793499100
DOI https://dx.doi.org/10.2174/157339910793499100 |
Print ISSN 1573-3998 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6417 |
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