Current Nanoscience

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Biocompatible Europium Doped Hydroxyapatite Nanoparticles as a Biological Fluorescent Probe

Author(s): Yingchao Han, Xinyu Wang, Shipu Li.

Abstract:

In this study, a cell labelling method is presented using biocompatible europium doped hydroxyapatite (Eu-HAP) inorganic nanoparticles. Eu-HAP nanoparticles were successfully prepared by precipitation method and utilized to label Bel-7402 human liver cancer cells as fluorescent probe. After Eu-HAP nanoparticles were internalized by cells, the strong green fluorescence and the red fluorescence were observed with excitation of blue light and green light respectively. Results show that the Eu-HAP nanoparticles exhibit the potential to become valuable biocompatible fluorescent labelling material in biological studies.

Keywords: Europium doped hydroxyapatite, Inorganic nanoparticles, Cell labelling, Fluorescent probe

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Article Details

VOLUME: 6
ISSUE: 2
Year: 2010
Page: [178 - 183]
Pages: 6
DOI: 10.2174/157341310790945632
Price: $58