Abstract
We report a significant increase of a curcumin (1,7-bis[4-hydroxy-3-methoxyphenyl]-1,6-heptadiene-3,5-dione) fluorescence brightness when deposited on plasmonic platforms (self assembled silver nanostructures formed on the surface of silver semitransparent film). The enhancement of fluorescence intensity is accompanied by a strong decrease in fluorescence lifetime. Simultaneously, the increased photostability of curcumin, a pigment showing strong antiinflammatory, antioxidant and antitumorigenic activity, allows long-time detection and monitoring. We believe that the use of plasmonic platforms will improve detection, delivery and imaging of curcumin.
Keywords: Fluorescence lifetime, metal enhanced fluorescence, photostability, plasmonic platforms, brightness, curcumin
Current Pharmaceutical Biotechnology
Title: Enhanced Fluorescence of Curcumin on Plasmonic Platforms
Volume: 11 Issue: 2
Author(s): Anindita Mukerjee, Rafal Luchowski, Amalendu P. Ranjan, Sangram Raut, Jamboor K. Vishwanatha, Zygmunt Gryczynski and Ignacy Gryczynski
Affiliation:
Keywords: Fluorescence lifetime, metal enhanced fluorescence, photostability, plasmonic platforms, brightness, curcumin
Abstract: We report a significant increase of a curcumin (1,7-bis[4-hydroxy-3-methoxyphenyl]-1,6-heptadiene-3,5-dione) fluorescence brightness when deposited on plasmonic platforms (self assembled silver nanostructures formed on the surface of silver semitransparent film). The enhancement of fluorescence intensity is accompanied by a strong decrease in fluorescence lifetime. Simultaneously, the increased photostability of curcumin, a pigment showing strong antiinflammatory, antioxidant and antitumorigenic activity, allows long-time detection and monitoring. We believe that the use of plasmonic platforms will improve detection, delivery and imaging of curcumin.
Export Options
About this article
Cite this article as:
Mukerjee Anindita, Luchowski Rafal, Ranjan P. Amalendu, Raut Sangram, Vishwanatha K. Jamboor, Gryczynski Zygmunt and Gryczynski Ignacy, Enhanced Fluorescence of Curcumin on Plasmonic Platforms, Current Pharmaceutical Biotechnology 2010; 11 (2) . https://dx.doi.org/10.2174/138920110790909623
DOI https://dx.doi.org/10.2174/138920110790909623 |
Print ISSN 1389-2010 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4316 |
Call for Papers in Thematic Issues
Artificial Intelligence in Bioinformatics
Bioinformatics is an interdisciplinary field that analyzes and explores biological data. This field combines biology and information system. Artificial Intelligence (AI) has attracted great attention as it tries to replicate human intelligence. It has become common technology for analyzing and solving complex data and problems and encompasses sub-fields of machine ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Ultrasound-Mediated Cancer Therapeutics Delivery using Micelles and Liposomes: A Review
Recent Patents on Anti-Cancer Drug Discovery Implications of Metal Nanoparticles on Aquatic Fauna: A Review
Nanoscience & Nanotechnology-Asia Progress Towards Clinically Useful Aldosterone Synthase Inhibitors
Current Topics in Medicinal Chemistry Phospho-Specific Antibodies: A Versatile Tool for Phosphoproteomic Studies
Current Proteomics Towards Computational Models of Identifying Protein Ubiquitination Sites
Current Drug Targets Management of Vulvar Cancer
Reviews on Recent Clinical Trials Hydroxamic Acids, Recent Breakthroughs in Stereoselective Synthesis and Biological Evaluations
Current Organic Synthesis Meet Our Editorial Board Member
Current Proteomics In Silico Studies of (2E,5E)-2,5-bis(3-methoxy-4-hydroxy-benzylidene) Cyclopentanone on Proteins AChE and BChE Involved in Alzheimers disease and Ameliorative Effects on Paraquat Induced Oxidative Stress Markers in Drosophila melanogaster
Letters in Drug Design & Discovery Recent Patents on Devices and Technologies for Early Cancer Diagnostics
Recent Patents on Biomedical Engineering (Discontinued) Therapeutic Drugs that Behave as Mechanism-Based Inhibitors of Cytochrome P450 3A4
Current Drug Metabolism Top-down and Bottom-up Approaches Revealed New Categories of Peptides from the Venom of Moroccan Scorpion <i>Androctonus mauretanicus</i>
Venoms and Toxins The Fabrication and Application of Bio-Functional Microspheres
Current Organic Chemistry The Metabolite Trimethylamine-N-Oxide is an Emergent Biomarker of Human Health
Current Medicinal Chemistry Knee Osteoarthritis and Exercise Adherence: A Review
Current Aging Science iLoc-Gpos: A Multi-Layer Classifier for Predicting the Subcellular Localization of Singleplex and Multiplex Gram-Positive Bacterial Proteins
Protein & Peptide Letters QSAR Studies of PTP1B Inhibitors: 1, 2-Naphthoquinone Derivatives
Letters in Drug Design & Discovery Recent Developments in Particulate-Based Vaccines
Recent Patents on Drug Delivery & Formulation Testicular Germ Cell Tumors: A Paradigm for the Successful Treatment of Solid Tumor Stem Cells
Current Cancer Therapy Reviews Toxicological Aspects of Carbon Nanotubes, Fullerenes and Graphenes
Current Pharmaceutical Design