Thermal-Assisted Refolding: Dilution Folding Initiated at High Temperature

Author(s): Kentaro Shiraki, Soichiro Kayano.

Journal Name: Current Pharmaceutical Biotechnology

Volume 11 , Issue 3 , 2010

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Abstract:

Protein refolding from unfolded state is usually carried out at low temperature to reduce protein aggregation and proteolytic degradation. This review briefly introduces a unique method for the protein refolding via high temperature, typically at above melting temperature of the protein.

Keywords: Inclusion bodies, protein refolding

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Article Details

VOLUME: 11
ISSUE: 3
Year: 2010
Page: [306 - 308]
Pages: 3
DOI: 10.2174/138920110791111988
Price: $58

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