Naturally Occurring δ-Hydroxy-γ-Lactones: Muricatacins and Related Compounds

Author(s): M. Carmen Murcia, Cristina Navarro, Ana Moreno, Aurelio G. Csaky.

Journal Name: Current Organic Chemistry

Volume 14 , Issue 1 , 2010

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Abstract:

In this account we present and critically analyze the different stereoselective synthetic strategies that have been reported in the literature for muricatacins [5-(1-hydroxytridecyl)dihydrofuran-2-ones], naturally occurring δ-hydroxy-γ-lactones related to acetogenins, which display cytotoxic activity towards human tumoral cell lines.

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Article Details

VOLUME: 14
ISSUE: 1
Year: 2010
Page: [15 - 47]
Pages: 33
DOI: 10.2174/138527210790226410

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