Review of Peak Detection Algorithms in Liquid-Chromatography-Mass Spectrometry

Author(s): Jianqiu Zhang, Elias Gonzalez, Travis Hestilow, William Haskins, Yufei Huang.

Journal Name: Current Genomics

Volume 10 , Issue 6 , 2009

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Abstract:

In this review, we will discuss peak detection in Liquid-Chromatography-Mass Spectrometry (LC/MS) from a signal processing perspective. A brief introduction to LC/MS is followed by a description of the major processing steps in LC/MS. Specifically, the problem of peak detection is formulated and various peak detection algorithms are described and compared.

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Article Details

VOLUME: 10
ISSUE: 6
Year: 2009
Page: [388 - 401]
Pages: 14
DOI: 10.2174/138920209789177638
Price: $58

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