Triglycerides and Cardiovascular Risk
K. E.L. Harchaoui, M. E. Visser, J. J.P. Kastelein, E. S. Stroes and G. M. Dallinga-Thie
Affiliation: Laboratory of Experimental Vascular Medicine, G1-113, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
Keywords: Triglycerides, coronary heart disease, lipoproteins, lipolytic enzymes
In 1996 a meta-analysis was published showing that an increase in plasma triglyceride (TG) levels was associated with an increase in CHD risk, even after adjustment for high density lipoprotein cholesterol (HDL-C) levels. Very recently, two studies were published that further extent the early observation and showed the importance of nonfasting plasma triglyceride (TG) levels in the prediction of risk on coronary heart disease (CHD). In the current review we have summarized all available evidence obtained in clinical studies showing that treatment guidelines should reconsider to include nonfasting TG in their risk assessments as nonfasting TG levels may better predict CVD risk.
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