Recent Progress on the Synthesis of Trifluoromethylated Heterocyclic Compounds Based on ethyl 4, 4, 4-trifluoroacetoacetate and its Derivatives

Author(s): Shizheng Zhu, Liping Song, Guifang Jin, Baifan Dai, Jian Hao.

Journal Name: Current Organic Chemistry

Volume 13 , Issue 10 , 2009

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Abstract:

This review highlights some of the recent progress that has been made in our laboratory and others in the field of trifluoromethylated (CF3) heterocyclic compounds starting from CF3-containing building blocks. Under mild reaction conditions, ethyl 4,4,4-trifluoroacetoacetate and its derivatives reacted with various organic reagents to produce CF3- containing N, O, S-heterocycles.

Keywords: Synthesis, trifluoromethylated (CF, ), ethyl 4, 4, 4-trifluoroacetoacetate, Derivatives, organic reagents

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Article Details

VOLUME: 13
ISSUE: 10
Year: 2009
Page: [1015 - 1027]
Pages: 13
DOI: 10.2174/138527209788680772
Price: $58

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