Anti-Cancer Agents in Medicinal Chemistry

(Formerly Current Medicinal Chemistry - Anti-Cancer Agents)

Michelle Prudhomme  
Universite Blaise Pascal - C.N.R.S
Aubiere Cedex
France

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Aromatase: The Enzyme and Its Inhibition

Author(s): Lee Banting, Sabbir Ahmed.

Abstract:

The genetic control, mechanism of action and inhibition of aromatase for potential therapeutic benefits in the arena of hormone dependent illness continues to be of considerable interest. The work presented here concentrates on recent advances in the mechanistic aspects of the aromatase enzyme and the nature of the chemical entities that lead to its inhibition.

Keywords: Aromatase, inhibition, enzyme, mechanism, natural products, heterocyclic, inhibitor

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Article Details

VOLUME: 9
ISSUE: 6
Page: [627 - 641]
Pages: 15
DOI: 10.2174/187152009788680037
Price: $58