The No-Reflow Phenomenon in the Coronary Circulation

Author(s): Thomas J. Kiernan, Nicholas J. Ruggiero II, Juan M. Bernal, Creighton W. Don, Christian Witzke, Gareth D. Kiernan, Roberto J. Cubeddu, Bryan P. Yan.

Journal Name: Cardiovascular & Hematological Agents in Medicinal Chemistry
(Formerly Current Medicinal Chemistry - Cardiovascular & Hematological Agents)

Volume 7 , Issue 3 , 2009

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Abstract:

The no-reflow phenomenon is a poorly understood complication of percutaneous coronary intervention in which diminished blood flow to distal microvascular beds persists despite the successful treatment of the occlusive lesion from the epicardial coronary artery or arteries. In this contemporary review we endeavour to discuss the pathophysiology of coronary no-reflow, understand the predictors and describe current pharmacological and mechanical strategies to prevent and treat coronary no-reflow.

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Article Details

VOLUME: 7
ISSUE: 3
Year: 2009
Page: [181 - 192]
Pages: 12
DOI: 10.2174/187152509789105426
Price: $58

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