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Combinatorial Chemistry & High Throughput Screening

Editor-in-Chief

ISSN (Print): 1386-2073
ISSN (Online): 1875-5402

Cell Interactions with Biomaterials Gradients and Arrays

Author(s): Carl G. Simon Jr., Yanyin Yang, Vinoy Thomas, Shauna M. Dorsey and Abby W. Morgan

Volume 12, Issue 6, 2009

Page: [544 - 553] Pages: 10

DOI: 10.2174/138620709788681961

Price: $65

Abstract

Gradients and arrays have become very useful to the fields of tissue engineering and biomaterials. Both gradients and arrays make efficient platforms for screening cell response to biomaterials. Graded biomaterials also have functional applications and make useful substrates for fundamental studies of cell phenomena such as migration. This article will review the use of gradients and arrays in tissue engineering and biomaterials research, with a focus on cellular and biologic responses.

Keywords: Biomaterials, cell adhesion, cell-material interactions, combinatorial screening, gradient, hydrogel, microarray, polymer, tissue engineering


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