Abstract
L-Ascorbic acid, commonly known as vitamin C is well-known in chemistry since long back. It has tremendous medical applications in several diseases. However, application of this chiral molecule in organic synthesis has been neglected earlier. In the later part of twentieth century application of ascorbic acid has gained momentum in organic synthesis of different molecules of biological importance and of chemotherapeutic significance. We have given an account of the history, chemistry, biochemistry and biosynthesis of ascorbic acid and application of this small molecule in organic synthesis. The application of ascorbic acid in accessing chiral synthons has also been described.
Keywords: Organic Synthesis, L-Ascorbic Acid, chiral molecule, biosynthesis, chemotherapeutic significance
Current Organic Chemistry
Title: L-Ascorbic Acid in Organic Synthesis: An Overview
Volume: 13 Issue: 1
Author(s): Rama Pati Tripathi, Biswajit Singh, Surendra Singh Bisht and Jyoti Pandey
Affiliation:
Keywords: Organic Synthesis, L-Ascorbic Acid, chiral molecule, biosynthesis, chemotherapeutic significance
Abstract: L-Ascorbic acid, commonly known as vitamin C is well-known in chemistry since long back. It has tremendous medical applications in several diseases. However, application of this chiral molecule in organic synthesis has been neglected earlier. In the later part of twentieth century application of ascorbic acid has gained momentum in organic synthesis of different molecules of biological importance and of chemotherapeutic significance. We have given an account of the history, chemistry, biochemistry and biosynthesis of ascorbic acid and application of this small molecule in organic synthesis. The application of ascorbic acid in accessing chiral synthons has also been described.
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Cite this article as:
Tripathi Pati Rama, Singh Biswajit, Bisht Singh Surendra and Pandey Jyoti, L-Ascorbic Acid in Organic Synthesis: An Overview, Current Organic Chemistry 2009; 13 (1) . https://dx.doi.org/10.2174/138527209787193792
DOI https://dx.doi.org/10.2174/138527209787193792 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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