Recent Trends in Plant-Derived Antifungal Agents

Author(s): M. Shahid, A. Shahzad, T. Tripathi, F. Sobia, A. Sahai, A. Singh, A. Malik, F. Shujatullah, H. M. Khan.

Journal Name:Anti-Infective Agents in Medicinal Chemistry

Volume 8 , Issue 1 , 2009


Recent years have witnessed emergence of resistance to azoles and other antifungal compounds. Moreover, the existing antifungal compounds for the contemporary clinicians are limited in numbers as opposed to available antibacterial compounds. Hence there is a real need to search for newer compounds with potential antifungal activity. In this review, the potential of medicinal plant species to yield newer antifungal agents would be illustrated with an emphasis on compounds discovered in recent years. Some of the issues pertinent to this area, including their botanical, medicinal, and available spectroscopic data, will briefly be reviewed and it is hoped that this would definitely stimulate for their discussions and researches on this important aspect including the mechanism of actions of these recently discovered compounds.

Keywords: Antifungal-potential, plant-derived, newer compounds, medicinal chemistry

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Article Details

Year: 2009
Page: [36 - 49]
Pages: 14
DOI: 10.2174/187152109787047788