Microarray: An Approach for Current Drug Targets

Author(s): Virendra S. Gomase, Somnath Tagore, Karbhari V. Kale.

Journal Name: Current Drug Metabolism

Volume 9 , Issue 3 , 2008

Abstract:

Microarrays are a powerful tool has multiple applications both in clinical and cellular and molecular biology arenas. Early assessment of the probable biological importance of drug targets, pharmacogenomics, toxicogenomics and single nucleotide polymorphisms (SNPs). A list of new drug candidates along with proposed targets for intervention is described. Recent advances in the knowledge of microarrays analysis of organisms and the availability of the genomics sequences provide a wide range of novel targets for drug design. This review gives different process of microarray technologies; methods for comparative gene expression study, applications of microarrays in medicine and pharmacogenomics and current drug targets in research, which are relevant to common diseases as they relate to clinical and future perspectives.

Keywords: Microarrays, DNA arrays, gene expression, oligonucleotide, IHC, FISH, biomarker

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Article Details

VOLUME: 9
ISSUE: 3
Year: 2008
Page: [221 - 231]
Pages: 11
DOI: 10.2174/138920008783884795
Price: $58

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