Models for Non-Alcoholic Fatty Liver Disease: A Link with Vascular Risk

Author(s): A. K. Burroughs, E. Xirouchakis, A. Sigalas, P. Manousou, V. Calvaruso, M. Pleguezuelo, A. Corbani, S. Maimone, D. Patch.

Journal Name: Current Pharmaceutical Design

Volume 14 , Issue 4 , 2008

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Abstract:

Non alcoholic fatty liver disease (NAFLD) is often part of the metabolic syndrome which includes central obesity, dyslipidaemia, insulin resistance/type 2 diabetes mellitus and hypertension. In turn, NAFLD may be associated with an increased vascular risk. Several experimental models which express histological steatosis or steatohepatitis with fibrosis have been described. This review identifies those models of NAFLD with features of vascular risk.

Keywords: Non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, vascular risk

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Article Details

VOLUME: 14
ISSUE: 4
Year: 2008
Page: [378 - 384]
Pages: 7
DOI: 10.2174/138161208783497705
Price: $58

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