Patterns of Insertion and Deletion in Mammalian Genomes

Author(s): Shiheng Tao, Yanhui Fan, Wenjuan Wang, Guoji Ma, Lijing Liang, Qi Shi.

Journal Name: Current Genomics

Volume 8 , Issue 6 , 2007

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Abstract:

Nucleotide insertions and deletions (indels) are responsible for gaps in the sequence alignments. Indel is one of the major sources of evolutionary change at the molecular level. We have examined the patterns of insertions and deletions in the 19 mammalian genomes, and found that deletion events are more common than insertions in the mammalian genomes. Both the number of insertions and deletions decrease rapidly when the gap length increases and single nucleotide indel is the most frequent in all indel events. The frequencies of both insertions and deletions can be described well by power law.

Keywords: Insertion, deletion, gap, indel, mammalian genome

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Article Details

VOLUME: 8
ISSUE: 6
Year: 2007
Page: [370 - 378]
Pages: 9
DOI: 10.2174/138920207783406479
Price: $58