Mechanisms of Intrinsic and Acquired Resistance to EGFR Inhibitors

Author(s): Floriana Morgillo, Giampaolo Tortora, Fortunato Ciardiello.

Journal Name: Current Cancer Therapy Reviews

Volume 3 , Issue 4 , 2007

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Abstract:

In the last decades the epidermal growth factor receptor (EGFR), which is frequently expressed in a variety of epithelial tumors, has been a major target of molecular anticancer therapy.

Keywords: EGFR, Monoclonal antibody, Tyrosine kinase inhibitor, resistance

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Article Details

VOLUME: 3
ISSUE: 4
Year: 2007
Page: [276 - 283]
Pages: 8
DOI: 10.2174/157339407782496988
Price: $58

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