Abstract
In the past several years, a new set of technologies based on whole genome analysis have revolutionized the study of gene expression. These microarray or “gene chip” technologies, which arose out of the development of large-scale sequencing approaches, are now coming into increasing use, generating a far greater volume of data than the data representing the sequences themselves. This review focuses on the current state of development of these technologies, and the available approaches to manage and analyze the information they generate. The applicability of this technology to general problems in biomedicine is also discussed.
Combinatorial Chemistry & High Throughput Screening
Title: High Throughput and Global Approaches to Gene Expression
Volume: 3 Issue: 5
Author(s): David Ghosh
Affiliation:
Abstract: In the past several years, a new set of technologies based on whole genome analysis have revolutionized the study of gene expression. These microarray or “gene chip” technologies, which arose out of the development of large-scale sequencing approaches, are now coming into increasing use, generating a far greater volume of data than the data representing the sequences themselves. This review focuses on the current state of development of these technologies, and the available approaches to manage and analyze the information they generate. The applicability of this technology to general problems in biomedicine is also discussed.
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Cite this article as:
Ghosh David, High Throughput and Global Approaches to Gene Expression, Combinatorial Chemistry & High Throughput Screening 2000; 3 (5) . https://dx.doi.org/10.2174/1386207003331481
DOI https://dx.doi.org/10.2174/1386207003331481 |
Print ISSN 1386-2073 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5402 |
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