Abstract
This review covers recent developments in the area of morphine synthesis and biosynthesis. Literature is reviewed since the publication of the last major review. The first part of the chapter discusses recent advancements in biosynthesis of morphine alkaloids. Total syntheses published since 1996 are reviewed next and the third section discusses all published approaches to morphine skeleton. At the end of the of the chapter, an additional reference list is provided for synthesis of medicinally important derivatives, improvements in alkoloid interconversion, as well as a list of all dissertations dealing with morphine synthesis.
Current Organic Chemistry
Title: Morphine Synthesis and Biosynthesis-An Update
Volume: 4 Issue: 3
Author(s): Bennett H. Novak, Tomas Hudlicky, Josephine W. Reed, Johann Mulzer and Dirk Trauner
Affiliation:
Abstract: This review covers recent developments in the area of morphine synthesis and biosynthesis. Literature is reviewed since the publication of the last major review. The first part of the chapter discusses recent advancements in biosynthesis of morphine alkaloids. Total syntheses published since 1996 are reviewed next and the third section discusses all published approaches to morphine skeleton. At the end of the of the chapter, an additional reference list is provided for synthesis of medicinally important derivatives, improvements in alkoloid interconversion, as well as a list of all dissertations dealing with morphine synthesis.
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Cite this article as:
Novak H. Bennett, Hudlicky Tomas, Reed W. Josephine, Mulzer Johann and Trauner Dirk, Morphine Synthesis and Biosynthesis-An Update, Current Organic Chemistry 2000; 4 (3) . https://dx.doi.org/10.2174/1385272003376292
DOI https://dx.doi.org/10.2174/1385272003376292 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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