Recent Advances in the Chemistry of Cyclic Peroxides

Author(s): Kevin J. McCullough, Masatomo Nojima.

Journal Name: Current Organic Chemistry

Volume 5 , Issue 6 , 2001

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The well-known antimalarial properties of naturally occurring cyclic peroxides artemisinin (qinghaosu), yingzhaosu A and yingzhaosu C have stimulated the development of new strategies for the synthesis of cyclic peroxides with diverse structures, and the investigation of the chemical transformations and properties of such compounds. In this review, recent progress in the chemistry of mono- and polycyclic organic peroxides with ring sizes of five or greater is highlighted and discussed.

Keywords: Cyclic Peroxides, artemisinin, photo-oxygenation, 1,2-DIOXOLANES, spirodioxolane, allylstannane, Alkoxy-1,2-dioxolanes, oxatrimethylene diradical, diastereoisomeric, hydroperoxide, aminophthalamide, TMSOTf-catalysed cyclocondensation, 1,4-bis(dihydroquinine)phthalazine, hexafluorophosphate, diisobutylaluminium hydride, N-iodosuccinimide, trimethylsilyl triflate, 2,2,6,6-tetramethyl-1-piperidinyloxy

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Article Details

Year: 2001
Page: [601 - 636]
Pages: 36
DOI: 10.2174/1385272013375346
Price: $58

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