Polymer-Supported Metal-Phosphine Complexes for use as Catalysts or Linkers in Medicinally-Oriented Organic Synthesis

Author(s): Nicholas E. Leadbeater.

Journal Name: Current Medicinal Chemistry

Volume 9 , Issue 23 , 2002

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Abstract:

Polymer-supported catalysts and reagents have found many uses in synthetic organic chemistry. This review discusses the preparation of polymer-supported phosphine ligands and organometallic complexes formed using these and highlights their use in reactions that are of particular interest to medicinal chemists. The scope of the review is limited to phosphine ligands and their metal complexes attached to derivitised polystyrene supports.

Keywords: polystyrene, polymer-supported catalysts, metal-phosphine complexes, organometallic catalysis, supported peptides, combinatorial catalysis

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Article Details

VOLUME: 9
ISSUE: 23
Year: 2002
Page: [2147 - 2171]
Pages: 25
DOI: 10.2174/0929867023368700
Price: $58

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