Automated Parallel Solid-Phase Synthesis of Non-Peptide CCR1 Receptor Antagonists

Author(s): Brad O. Buckman, Ameen Ghannam, Angela Li, Meina Liang, Raju Mohan, Howard P. Ng.

Journal Name: Combinatorial Chemistry & High Throughput Screening

Volume 5 , Issue 3 , 2002

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Abstract:

An automated, parallel, solid-phase synthesis and screening strategy using commercially available aryl acetic acids as starting materials has discovered novel, non-peptide CCR1 antagonists (Ki < 100 nM).

Keywords: solid-phase synthesis, ccri receptor antagonist

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Article Details

VOLUME: 5
ISSUE: 3
Year: 2002
Page: [249 - 251]
Pages: 3
DOI: 10.2174/1386207024607284
Price: $58

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