Synthesis of Trifluoromethyl Ketones Using Polymer-Supported Reagents

Author(s): I. R. Baxendale, S. V. Ley, W. Lumeras, M. Nesi.

Journal Name: Combinatorial Chemistry & High Throughput Screening

Volume 5 , Issue 3 , 2002

Become EABM
Become Reviewer

Abstract:

A two step synthesis of trifluoromethyl ketones from aldehydes is reported. A combination of polymer-supported reagents and sequestering agents were employed to effect the transformation without the need for chromatographic purification.

Keywords: polymer-supported reagent, sequestering agent, multi-parallel synthesis

Rights & PermissionsPrintExport Cite as


Article Details

VOLUME: 5
ISSUE: 3
Year: 2002
Page: [197 - 199]
Pages: 3
DOI: 10.2174/1386207024607220
Price: $58

Article Metrics

PDF: 4