Gene Regulation in Cancer Gene Therapy Strategies

Author(s): Ian Scanlon , Panos Lehouritis , Ion Niculescu-Duvaz , Richard Marais , Caroline J. Springer .

Journal Name: Current Medicinal Chemistry

Volume 10 , Issue 20 , 2003

Abstract:

Regulation of expression in gene therapy is considered to be a very desirable goal, preventing toxic effects and improving biological efficacy. A variety of systems have been reported in an ever widening range of applications, this paper describes these systems with specific reference to cancer gene therapy.

Keywords: transcriptional control, regulated expression, gdept, suicide gene

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Article Details

VOLUME: 10
ISSUE: 20
Year: 2003
Page: [2175 - 2184]
Pages: 10
DOI: 10.2174/0929867033456837
Price: $58