Abstract
Our ability to study thousands of genes simultaneously over the last few years owing not only to the development of DNA microarray technology, but also to large-scale yeast two-hybrid and other methods, has brought about a paradigmatic shift in biology. Armed with the complete sequences of several genomes including humans, more and more biomedical investigators are now interested in understanding the functions of gene products, or proteins, on a global scale. In this article, the promises and pitfalls of two methods used for proteomics studies - protein microarrays and mass spectrometry - towards achieving this goal are discussed.
Keywords: paradigmatic, protein microarrays, spectrometry, genomes, Proteomics
Current Genomics
Title: Microarrays and Mass Spectrometry - The Future of Proteomics
Volume: 4 Issue: 7
Author(s): K. S. Deshpande, H. C. Harsha and A. Pandey
Affiliation:
Keywords: paradigmatic, protein microarrays, spectrometry, genomes, Proteomics
Abstract: Our ability to study thousands of genes simultaneously over the last few years owing not only to the development of DNA microarray technology, but also to large-scale yeast two-hybrid and other methods, has brought about a paradigmatic shift in biology. Armed with the complete sequences of several genomes including humans, more and more biomedical investigators are now interested in understanding the functions of gene products, or proteins, on a global scale. In this article, the promises and pitfalls of two methods used for proteomics studies - protein microarrays and mass spectrometry - towards achieving this goal are discussed.
Export Options
About this article
Cite this article as:
Deshpande S. K., Harsha C. H. and Pandey A., Microarrays and Mass Spectrometry - The Future of Proteomics, Current Genomics 2003; 4 (7) . https://dx.doi.org/10.2174/1389202033490213
DOI https://dx.doi.org/10.2174/1389202033490213 |
Print ISSN 1389-2029 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5488 |
Call for Papers in Thematic Issues
Advanced Computational Algorithms and Artificial Intelligence in Clinical Pharmacogenomics
In the era of personalized medicine, understanding the relationship between genetics and drug response is crucial. This issue delves into innovative methodologies, leveraging deep computational analysis and artificial intelligence, to enhance the field of Clinical Pharmacogenomics. The interdisciplinary approach harnesses the power of advanced high-throughput genotyping technologies, sophisticated computational analysis, ...read more
Applications of Single-cell Sequencing Technology in Reproductive Medicine
Single cell sequencing (SCS) technology utilizes individual cells' genetic material to sequence their genome, transcriptome, and epigenetics at the molecular level. It offers insights into cell heterogeneity and enables the study of limited biological materials. Since its recognition as a valuable technique in 2011, single cell sequencing has yielded numerous ...read more
Big Data in Cancer Research
Cancer is a significant threat to human life and health, remaining a highly aggressive killer. It is a leading cause of death worldwide and represents a crucial medical issue for humanity. However, in the past decade, the effectiveness of new synthetic anticancer agents has not matched the current clinical speculation. ...read more
Current Genomics in Cardiovascular Research
Cardiovascular diseases are the main cause of death in the world, in recent years we have had important advances in the interaction between cardiovascular disease and genomics. In this Research Topic, we intend for researchers to present their results with a focus on basic, translational and clinical investigations associated with ...read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Improving Carotenoids and Amino-Acids in Cassava
Recent Patents on Food, Nutrition & Agriculture Targeting the PI3K/AKT/mTOR Signaling Pathway in Medulloblastoma
Current Molecular Medicine Recent Progress in the Development of Quinoline Derivatives for the Exploitation of Anti-Cancer Agents
Anti-Cancer Agents in Medicinal Chemistry Signal Transduction Therapy Targeting Apoptosis Pathways in Cancers
Current Signal Transduction Therapy Kinetic and Structural Studies on the Interactions of Heparin and Proteins of Human Seminal Plasma using Surface Plasmon Resonance
Protein & Peptide Letters Complexity in Clinical Trials: Blind Spots, Misleading Criteria, Winners and Losers
Clinical Cancer Drugs The Use of Intravenous Aminobisphosphonates for the Treatment of Pagets Disease of Bone
Mini-Reviews in Medicinal Chemistry Chemical Characterization of Phytochemicals of Cucurbitaceae Family by Gas Chromatography – Mass Spectroscopy
Current Traditional Medicine Oleuropein Mediated Targeting of Signaling Network in Cancer
Current Topics in Medicinal Chemistry Patents Related to Cancer Stem Cell Research
Recent Patents on DNA & Gene Sequences Discovery of Novel CYP17 Inhibitors for the Treatment of Prostate Cancer with Structure-Based Drug Design
Letters in Drug Design & Discovery Cathepsin D as a Promising Target for the Discovery of Novel Anticancer Agents
Current Cancer Drug Targets Regulation of Mammalian UDP-Glucuronosyltransferases
Current Drug Metabolism Anti-tumor Drug Targets Analysis: Current Insight and Future Prospect
Current Drug Targets Food and Food Supplements with Hypocholesterolemic Effects
Recent Patents on Food, Nutrition & Agriculture Epidermal Growth Factor Receptor and its Trafficking Regulation by Acetylation: Implication in Resistance and Exploring the Newer Therapeutic Avenues in Cancer
Current Topics in Medicinal Chemistry Angiogenesis Inhibition: State of the Art, Forgotten Strategies and New Perspectives in Cancer Therapy
Current Cancer Therapy Reviews Discovery of Multi-target Anticancer Agents Based on HDAC Inhibitor MS-275 and 5-FU
Medicinal Chemistry On the Relationship Between the Light/Dark Cycle, Melatonin and Oxidative Stress
Current Pharmaceutical Design Small Animal Computed Tomography Imaging
Current Medical Imaging