Lithiated α-Chloroalkylheterocycles: Utility in Synthetic Organic Chemistry

Author(s): Saverio Florio, Vito Capriati, Renzo Luisi.

Journal Name: Current Organic Chemistry

Volume 8 , Issue 16 , 2004

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Abstract:

The chemistry of lithiated α-chloroalkylheterocycles such as α-chloroalkylbenzothiazoles, - benzotriazoles, -pyridines, -triazines, -thiazoles and -oxazolines has been reviewed. The synthetic application of this kind of chemistry for the stereoselective preparation of heteroaryl cyclopropanes, oxiranes, aziridines, alkenes and functionalised nitroarenes through a Darzens-type reaction, has been especially emphasised.

Keywords: carbenoids, haloalkyllithiums, chemistry, reagents, reactions, ring expansion, heterocyclic ring

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Article Details

VOLUME: 8
ISSUE: 16
Year: 2004
Page: [1529 - 1545]
Pages: 17
DOI: 10.2174/1385272043369719
Price: $58

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