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Current Pharmaceutical Design

Editor-in-Chief

ISSN (Print): 1381-6128
ISSN (Online): 1873-4286

Targeting the Assembly of the Human Immunodeficiency Virus Type I

Author(s): D. Muriaux, J. L. Darlix and A. Cimarelli

Volume 10, Issue 30, 2004

Page: [3725 - 3739] Pages: 15

DOI: 10.2174/1381612043382701

Price: $65

Abstract

In the rush to develop anti-viral drugs against the human immunodeficiency virus type I (HIV-1), all the steps of the viral life cycle are potential targets of therapeutic intervention. In this review, we will explore the recent advances on strategies that aim at obstructing the formation, the release and the infectivity of newly formed virion particles from HIV-1 infected cells.

Keywords: drugs, anti-viral approaches, virion assembly, hiv-1, retrovirus


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