Carbohydrates: From ‘Chirons’ to New Glycosubstances

Author(s): G. V.M. Sharma, Palakodety Radha Krishna.

Journal Name: Current Organic Chemistry

Volume 8 , Issue 13 , 2004

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Abstract:

Synthesis of C-glycosides, C-linked saccharides and new glycosubstances has been the subject of considerable interest in carbohydrate, enzymatic and metabolic chemistry, since some of such compounds exhibit exciting biological properties. As a consequence, the design and implementation of stereo selective strategies for preparing bio-active carbohydrates became a prominent issue. This article is mainly aimed at the presentation of the research findings of our group on the synthesis of C-alkyl and C-aryl glycosides, higher sugars; ‘de novo’ construction of disaccharides from furanyl and propargyl sugars; [3+3] annulation routes to carbocycles and pseudo saccharides; 1,3-dipolar cycloaddition to isoxazolidine sugars and saccharides; radical routes to spiro acetal saccharides and ulosonic acid derivatives.

Keywords: Carbohydrates, 1,3-dipolar cycloaddition, spiro acetal saccharides, C-aryl glycosides

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Article Details

VOLUME: 8
ISSUE: 13
Year: 2004
Page: [1187 - 1209]
Pages: 23
DOI: 10.2174/1385272043370096
Price: $58

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