Prospects for Atomic Resolution and Neutron Crystallography in Drug Design | BenthamScience

Prospects for Atomic Resolution and Neutron Crystallography in Drug Design

Author(s): L. Coates, D. A. A.Myles.

Journal Name: Current Drug Targets

Volume 5 , Issue 2 , 2004

Abstract:

The number of protein crystal structures being refined to atomic resolution is increasing each year as well as the size of proteins being studied. There are currently 346 structures in the protein data bank which have been refined to or beyond atomic resolution. The benefits of atomic resolution X-ray data are discussed along with a number of structural examples of biomedically relevant proteins. The complementary role of neutron diffraction will also be discussed.

Keywords: Neutron Crystallography, atomic resolution, X-ray

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Article Details

VOLUME: 5
ISSUE: 2
Year: 2004
Page: [173 - 178]
Pages: 6
DOI: 10.2174/1389450043490613
Price: $58

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