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Current Medicinal Chemistry
ISSN (Print): 0929-8673
ISSN (Online): 1875-533X
VOLUME: 11
ISSUE: 15
DOI: 10.2174/0929867043364810      Price:  $58









Monoamine Oxidases: Certainties and Uncertainties

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Author(s): Keith F. Tipton, Sinead Boyce, Jeff O'Sullivan, Gavin P. Davey and Joe Healy
Pages 1965-1982 (18)
Abstract:
A great deal has been learned about the behaviour of monoamine oxidase in the 75 years since it was first discovered, but there is still a great deal left to understand. This review concentrates on the dynamic aspects of our knowledge of the interactions of MAO with substrates and inhibitors and how it may collaborate with other enzymes, with particular emphasis on aspects that remain to be clarified.
Keywords:
monoamine oxidases, substrates, inhibitors
Affiliation:
Department of Biochemistry, Trinity College, Dublin 2, Ireland