Current Cancer Therapy Reviews

Kurt S. Zaenker
Institute of Immunology and Experimental Oncology University Witten/Herdecke
Stockumerstraße 10, 58448 Witten
Germany

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Membrane Receptor and Antiangiogenic Targeted Therapies in the Treatment of Cancer

Author(s): Antonio Jimeno, Hernán Cortes-Funes.

Abstract:

The rapidly expanding knowledge of the pathogenesis of a variety of forms of cancer at the molecular level is now providing new targets for drug discovery and development. This has enabled us to successfully develop rationally designed therapies for cancer patients, and the results of their clinical evaluation are now becoming available. The optimal clinical development of target-based anticancer drugs will require fundamental changes to the way trials are designed, outcome is evaluated, and patients are selected to receive therapy. A thorough knowledge of what is accomplished so far is the cornerstone to optimally develop and implement these new strategies.

Keywords: targeted therapy, egfr, her2, vegfr

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Article Details

VOLUME: 1
ISSUE: 1
Year: 2005
Page: [51 - 61]
Pages: 11
DOI: 10.2174/1573394052952519