Syntheses of Hydroxylated Cyclic β-Amino Acid Derivatives

Author(s): Marta Palko, Lorand Kiss, Ferenc Fulop.

Journal Name: Current Medicinal Chemistry

Volume 12 , Issue 26 , 2005

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Abstract:

This review is intended to give a short summary of the developments in the field of natural and synthetic alicyclic and heterocyclic hydroxylated β-amino acids and to focus on the main strategies that have been reported for their synthesis. Given the medicinal and biological significance of the hydroxylated β-amino acids, an increasing volume of research is currently being directed toward regio-, stereo- and enantioselective access to this class of compounds.

Keywords: β-amino acids, peptides, asymmetric synthesis, selective functionalization

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Article Details

VOLUME: 12
ISSUE: 26
Year: 2005
Page: [3063 - 3083]
Pages: 21
DOI: 10.2174/092986705774933443
Price: $58

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