Pyrroloiminoquinone Alkaloids: Discorhabdins and Makaluvamines

Author(s): Yu Harayama, Yasuyuki Kita.

Journal Name: Current Organic Chemistry

Volume 9 , Issue 15 , 2005

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Abstract:

The pyrroloiminoquinone alkaloid family consisting of discorhabdins and makaluvamines exhibits antitumor activities derived from their unique highly-fused structures. The total synthesis of them and the key reactions used in the total synthesis of these compounds are described.

Keywords: discorhabdin c, yamamura's synthesis, heathcock's synthesis, white's formal synthesis, makaluvamine a, kraus's synthesis

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Article Details

VOLUME: 9
ISSUE: 15
Year: 2005
Page: [1567 - 1588]
Pages: 22
DOI: 10.2174/138527205774370568
Price: $58

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