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Current Cancer Therapy Reviews
ISSN (Print): 1573-3947
ISSN (Online): 1875-6301
VOLUME: 1
ISSUE: 2
DOI: 10.2174/1573394054021772      Price:  $58









Garlic and its Organosulfides as Potential Chemopreventive Agents: A Review

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Author(s): Annu Arora, Chitra Tripathi and Yogeshwer Shukla
Pages 199-205 (7)
Abstract:
There are many biological plausible reasons, which showed that plant food could prevent/delay the appearance of many diseases including cancer. Garlic has been reported to possess therapeutic properties from centuries and is probably the most widely studied medicinal plant. Garlic contains a number of organosulfur compounds such as SAC, S-allyl mercaptocysteine, allicin, ajoene, DAS and other structurally related compounds, which are widely believed to be active agents in preventing cancer. Epidemiological as well as experimental studies have provided sufficient evidences that garlic along with its organosulfur components possess pleiotropic beneficial health effects including antioxidative, antimutagenic and anti-tumorigenic properties.
Keywords:
garlic, organosulfur compounds, cancer, antioxidative, antimutagenic, antitumorigenic
Affiliation:
Environmental Carcinogenesis Division, Industrial Toxicology Research Centre, P.O. Box 80, M.G. Marg, Lucknow-226001, India.