Current Medicinal Chemistry

Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge
Cambridge
UK

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Positron-Emitting Isotopes Produced on Biomedical Cyclotrons

Author(s): Paul McQuade, Douglas J. Rowland, Jason S. Lewis and Michael J. Welch

Affiliation: Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S. Kingshighway Boulevard, Campus Box 8225, Saint Louis, MO 63110; USA.

Keywords: positron emission tomography, radionuclides, micropet, production methods, radioisotopes

Abstract:

This review will discuss the production and applications of positron-emitting radionuclides for use in Positron Emission Tomography (PET), with emphasis on radionuclides that can be produced onsite with a biomedical cyclotron. In PET the traditional radionuclides of choice are 11C, 13N, 15O and 18F and although they will be briefly discussed in this article, the emphasis of this review will be on non-standard PET radionuclides that are generating increased interest by the medical research community.

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Article Details

VOLUME: 12
ISSUE: 7
Page: [807 - 818]
Pages: 12
DOI: 10.2174/0929867053507397