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Current Medicinal Chemistry
ISSN (Print): 0929-8673
ISSN (Online): 1875-533X
VOLUME: 12
ISSUE: 7
DOI: 10.2174/0929867053507324      Price:  $58









Fluorescence Imaging of Tumors In Vivo

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Author(s): Byron Ballou, Lauren A. Ernst and Alan S. Waggoner
Pages 795-805 (11)
Abstract:
We review recent progress in tumor imaging in vivo using fluorescent tags, highlight the problems of fluorescence imaging in small animals, discuss recent advances in near-infrared fluorochromes and quantum dots, and point to some future possibilities. GFP-based fluorescence imaging is briefly discussed. The authors believe that improvements in near-infrared fluorochromes are required to enable practical imaging in tissues at centimeter depths.
Keywords:
animals, antibodies, monoclonal, antigens, neoplasm, fluorescent dyes, green fluorescent protein, imaging, nanotechnology, quantum dots
Affiliation:
Molecular Biosensor and Imaging Center, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213, USA.