Fluorescence Imaging of Tumors In Vivo

Author(s): Byron Ballou, Lauren A. Ernst, Alan S. Waggoner.

Journal Name: Current Medicinal Chemistry

Volume 12 , Issue 7 , 2005

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We review recent progress in tumor imaging in vivo using fluorescent tags, highlight the problems of fluorescence imaging in small animals, discuss recent advances in near-infrared fluorochromes and quantum dots, and point to some future possibilities. GFP-based fluorescence imaging is briefly discussed. The authors believe that improvements in near-infrared fluorochromes are required to enable practical imaging in tissues at centimeter depths.

Keywords: animals, antibodies, monoclonal, antigens, neoplasm, fluorescent dyes, green fluorescent protein, imaging, nanotechnology, quantum dots

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Article Details

Year: 2005
Page: [795 - 805]
Pages: 11
DOI: 10.2174/0929867053507324
Price: $58

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