Dual Action-Based Approaches to Antibacterial Agents

Author(s): John B. Bremner, Joseph I. Ambrus, Siritron Samosorn.

Journal Name:Current Medicinal Chemistry

Volume 14 , Issue 13 , 2007

Abstract:

This review collates and analyses recent work done on dual action approaches to tackling the mounting health problem of resistance by human pathogenic bacteria to antibacterial agents. In particular the areas reviewed include the use of two drugs in combination, dual action prodrugs, and dual action drugs (or hybrid drugs)

Keywords: Dual action antibacterials, bacterial resistance, dual action drugs, dual action prodrugs

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Article Details

VOLUME: 14
ISSUE: 13
Year: 2007
Page: [1459 - 1477]
Pages: 19
DOI: 10.2174/092986707780831168
Price: $58