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Current Medicinal Chemistry
ISSN (Print): 0929-8673
ISSN (Online): 1875-533X
VOLUME: 14
ISSUE: 13
DOI: 10.2174/092986707780831168      Price:  $58









Dual Action-Based Approaches to Antibacterial Agents

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Author(s): John B. Bremner, Joseph I. Ambrus and Siritron Samosorn
Pages 1459-1477 (19)
Abstract:
This review collates and analyses recent work done on dual action approaches to tackling the mounting health problem of resistance by human pathogenic bacteria to antibacterial agents. In particular the areas reviewed include the use of two drugs in combination, dual action prodrugs, and dual action drugs (or hybrid drugs)
Keywords:
Dual action antibacterials, bacterial resistance, dual action drugs, dual action prodrugs
Affiliation:
Department of Chemistry,University of Wollongong, Wollongong, NSW, 2522, Australia.