Current Medicinal Chemistry

Atta-ur-Rahman, FRS
Honorary Life Fellow
Kings College
University of Cambridge


A Review on Synthetic and Natural Steroid Dimers: 1997-2006

Author(s): L. Nahar, S. D. Sarker and A. B. Turner

Affiliation: School of Biomedical Sciences, University of Ulster at Coleraine, Cromore Road, Coleraine BT52 1SA, Co. Londonderry,Northern Ireland, UK.


Since the publication of the review by Li and Dias in 1997, which covered almost all steroid dimers known to us until the early part of 1997, there have been significant amounts of work carried out on steroid dimers, and another review on this topic has long been overdue. Thus, this review presents a comprehensive review of literature published over the last decade on various aspects of steroid dimers, including synthesis and applications. Steroid dimers that were published before 1997 but were not covered within the previous review have also been included.

Keywords: Steroids dimer, synthesis, molecular umbrella, anticancer, cephalostatins, ritterazines, crellastatins, natural product

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Article Details

Page: [1349 - 1370]
Pages: 22
DOI: 10.2174/092986707780597880