Bioluminescence tomography (BLT) is a new molecular imaging tool. Using a modality fusion approach, we built the first BLT prototype that combines BLI data and micro-CT and micro-MRI images for proof of concept, established a theoretical framework for BLT, and reported encouraging preliminary results. In this overview, we highlight our key results and discuss further directions.
Keywords: Bioluminescence imaging, Bioluminescence tomography, Finite Element Method, Monte Carlo approach, Molecular optical simulation environment, Multi-spectral signal separation
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