Recent Development in Bioluminescence Tomography
Ge Wang, Xin Qian, Wenxiang Cong, Haiou Shen, Yi Li, Weimin Han, Kumar Durairaj, Ming Jiang, Tie Zhou, Jiantao Cheng, Jie Tian, Yujie Lv, Hui Li and Jie Luo
Affiliation: 200 Hawkins Drive, UIHC, 3970 JPP, University of Iowa, Iowa City, IA 52242, USA.
Bioluminescence tomography (BLT) is a new molecular imaging tool. Using a modality fusion approach, we built the first BLT prototype that combines BLI data and micro-CT and micro-MRI images for proof of concept, established a theoretical framework for BLT, and reported encouraging preliminary results. In this overview, we highlight our key results and discuss further directions.
Keywords: Bioluminescence imaging, Bioluminescence tomography, Finite Element Method, Monte Carlo approach, Molecular optical simulation environment, Multi-spectral signal separation
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