Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry

(Formerly Current Medicinal Chemistry - Anti-Inflammatory and Anti-Allergy Agents)

Bahar Tunctan
Department of Pharmacology
Faculty of Pharmacy
Mersin University
Mersin, 33169
Turkey

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Anti-Inflammatory Agents in Ageing and Age-Associated Diseases

Author(s): S. Bonovas, N. M. Sitaras.

Abstract:

Ageing and inflammation might be considered as natural partners. Numerous mechanisms of an inflammatory basis for several age-associated diseases have been identified. Some markers of inflammation are already being integrated into clinical medicine. Furthermore, existent anti-inflammatory drugs and novel candidates have been found to specifically target inflammation pathways in the ageing processes. In this review, we focus on the current knowledge on the field, from the molecular and cellular level to the therapeutic potential of anti-inflammatory agents. First, we present several theories of ageing, in order to explore the involvement of inflammation and to define targets of intervention. Then, we discuss the current approaches and applications as well as the future trends in research regarding the involvement of antiinflammatory agents in the ageing processes.

Keywords: Ageing, anti-inflammatory agents, inflammation

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Article Details

VOLUME: 5
ISSUE: 4
Year: 2006
Page: [365 - 373]
Pages: 9
DOI: 10.2174/187152306778772856
Price: $58