Anti-Cancer Agents in Medicinal Chemistry

Cancer is classified as a complex and heterogeneous collection of disease with over 100 different types of cancer. Numerous medicinal plants have been reported to have anticancer effect and effort for finding new anticancer agents with better efficacy and lesser side effects is still going on. Due to increasing cost of drug development, there is an urgent need for innovative approaches for target identification and efficacy prediction to uncover the therapeutic effect of drugs. A network-based approach is expected to offer important insights into the relationship between plants based active products and anticancer targets. In recent times, a renewed interest in understanding metabocentric adaptation occurring in the cancer cells vis-à-vis inflammation, angiogenesis and metastasis has been observed. Given the functional interdependencies between anti-cancer molecular targets and phytochemicals, emerging tools of network medicine offer a platform to explore systematically complexity of cancer biology, drug targets and therapeutic use of phytochemicals. In the special issue we invite the researchers to contribute original and review articles regarding network-based drug discovery, anti-cancer molecular targets and therapeutic use of phytochemicals

To give an overview of current indications and criticism on Active Surveillance for prostate cancer and small renal masses

Aims & Scope: In spite of the major progress made in the medical world to treat cancer, the existing therapies lack in terms of selectivity, and some cancers are infact resistant to the existing therapies. Plasma treatment is gaining increasing interest, because it is stated to selectively treat cancer cells, and no resistance against plasma treatment has been observed yet. Most studies are still in vitro and in vivo and few existing clinical trials. Cold atmospheric plasma activated solution, on the other hand, can more generally be used where cold atmospheric plasma (CAP) device is not available, and it is also less dependent on the treatment conditions. Additionally, Cold atmospheric plasma activated solution can be injected into the tissues and thus prevent tumor growth more effectively than CAP devices. This special issue will help increase the understanding about the underlying mechanisms of Cold atmospheric plasma activated solution, but also enhance the possibilities to apply plasma medicine for cancer therapy.

Aims & Scope: The mini-hot topic issue will include reviews about both natural and chemical compounds used for the chemoprevention of different types of cancer. Mechanism of action will be discussed, including the antiproliferative, pro-apoptotic and inflammation-associated cancerogenesis. A special direction will be held towards mitochondria-targeted anticancer agents.A review of a new modern method of topical administration for antitumor skin active compounds, namely electoporation will be also depicted. The aims & scope of this special issue is to describe the latest news and trends in various types of cancer chemopreventive. An important place in this overview is allocated for skin cancer

No Text Found

No Text Found

No Text Found