Anti-Cancer Agents in Medicinal Chemistry

To give an overview of current indications and criticism on Active Surveillance for prostate cancer and small renal masses

Aims & Scope: In spite of the major progress made in the medical world to treat cancer, the existing therapies lack in terms of selectivity, and some cancers are infact resistant to the existing therapies. Plasma treatment is gaining increasing interest, because it is stated to selectively treat cancer cells, and no resistance against plasma treatment has been observed yet. Most studies are still in vitro and in vivo and few existing clinical trials. Cold atmospheric plasma activated solution, on the other hand, can more generally be used where cold atmospheric plasma (CAP) device is not available, and it is also less dependent on the treatment conditions. Additionally, Cold atmospheric plasma activated solution can be injected into the tissues and thus prevent tumor growth more effectively than CAP devices. This special issue will help increase the understanding about the underlying mechanisms of Cold atmospheric plasma activated solution, but also enhance the possibilities to apply plasma medicine for cancer therapy.

Aims & Scope: The mini-hot topic issue will include reviews about both natural and chemical compounds used for the chemoprevention of different types of cancer. Mechanism of action will be discussed, including the antiproliferative, pro-apoptotic and inflammation-associated cancerogenesis. A special direction will be held towards mitochondria-targeted anticancer agents.A review of a new modern method of topical administration for antitumor skin active compounds, namely electoporation will be also depicted. The aims & scope of this special issue is to describe the latest news and trends in various types of cancer chemopreventive. An important place in this overview is allocated for skin cancer

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