Current HIV Research

Charles Wood  
University of Nebraska
Lincoln, NE
USA

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Metabolic and Cardiovascular Complications of Highly Active Antiretroviral Therapy for HIV Infection

Author(s): Giuseppe Barbaro

Affiliation: Viale Anicio Gallo 63,00174 Rome, Italy.

Abstract:

Highly active antiretroviral therapy (HAART) regimens, especially those including protease inhibitors have been shown to cause, in a high proportion of HIV-infected patients, a metabolic syndrome (lipodystrophy/lipoatrophy, dyslipidemia, type 2 diabetes mellitus, insulin resistance) that may be associated with an increased risk of cardiovascular disease. A careful stratification of the cardiovascular risk of HIVinfected patients under HAART is needed according to the most recent clinical guidelines.

Keywords: Human immunodeficiency virus, highly active antiretroviral therapy, nucleoside reverse transcriptase inhibitors, protease inhibitors, metabolic syndome, cardiovascular disease

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Article Details

VOLUME: 4
ISSUE: 1
Page: [79 - 85]
Pages: 7
DOI: 10.2174/157016206775197664