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Current HIV Research
ISSN (Print): 1570-162X
ISSN (Online): 1873-4251
VOLUME: 4
ISSUE: 1
DOI: 10.2174/157016206775197664









Metabolic and Cardiovascular Complications of Highly Active Antiretroviral Therapy for HIV Infection

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Author(s): Giuseppe Barbaro
Pages 79-85 (7)
Abstract:
Highly active antiretroviral therapy (HAART) regimens, especially those including protease inhibitors have been shown to cause, in a high proportion of HIV-infected patients, a metabolic syndrome (lipodystrophy/lipoatrophy, dyslipidemia, type 2 diabetes mellitus, insulin resistance) that may be associated with an increased risk of cardiovascular disease. A careful stratification of the cardiovascular risk of HIVinfected patients under HAART is needed according to the most recent clinical guidelines.
Keywords:
Human immunodeficiency virus, highly active antiretroviral therapy, nucleoside reverse transcriptase inhibitors, protease inhibitors, metabolic syndome, cardiovascular disease
Affiliation:
Viale Anicio Gallo 63,00174 Rome, Italy.