C7-Substituted Estranes and Related Steroids

Author(s): Goreti Ribeiro Morais, Naho Yoshioka, Masataka Watanabe, Shuntaro Mataka, Cristina das Neves Oliveira, Thies Thiemann.

Journal Name: Mini-Reviews in Organic Chemistry

Volume 3 , Issue 3 , 2006

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Abstract:

C7-substituted steroids, especially C7-substituted estradiol derivatives, have been the subject of intensive interdisciplinary studies encompassing the fields of chemistry, biochemistry and medicine. While showing the more pertinent structures with their physiological characteristics, this review will focus on the synthetic approaches to these molecules.

Keywords: Steroids, estrogens, antiestrogens, estradiol, radiodiagnostics, breast cancer

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Article Details

VOLUME: 3
ISSUE: 3
Year: 2006
Page: [229 - 251]
Pages: 23
DOI: 10.2174/1570193X10603030229
Price: $58