Potential for Discovery of Neuroprotective Factors in Serum and Tissue from Hibernating Species

Author(s): Austin P.Ross, Kelly L.Drew.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 6 , Issue 8 , 2006

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Abstract:

Hibernation is a unique phenotype displayed by a phylogenetically diverse group of organisms including several species of mammals and one species of primate. Here we review evidence for blood and tissue borne signaling molecules in hibernating animals, achievements in isolating and characterizing these molecules, and potential medicinal applications.

Keywords: Heterothermic, Cytoprotective, Tolerance, Hibernation induction trigger, Endogenous factors, Metabolic suppression, Suspended animation, Plasma factors

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Article Details

VOLUME: 6
ISSUE: 8
Year: 2006
Page: [875 - 884]
Pages: 10
DOI: 10.2174/138955706777934964
Price: $58

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