The Stability Curve of Hen Egg White Lysozyme

Author(s): Saronya S. Younvanich, B. Mark Britt.

Journal Name: Protein & Peptide Letters

Volume 13 , Issue 8 , 2006

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Abstract:

The physiological stability curve -- a plot of the free energy of unfolding versus temperature -- is calculated for hen egg white lysozyme from a combination of extrapolated unfolding thermodynamic data from reversible conditions and isothermal titrations with guanidine hydrochloride. The shape of the curve suggests the existence of only one folded conformation.

Keywords: differential scanning calorimetry (DSC), protein stability, Titration, Gibbs-Helmholtz equation, lysozyme stability, guanidine hydrochloride

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Article Details

VOLUME: 13
ISSUE: 8
Year: 2006
Page: [769 - 772]
Pages: 4
DOI: 10.2174/092986606777841163
Price: $58

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