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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Function and Molecular Mechanism of Tumor-Targeted Peptides for Delivering Therapeutic Genes and Chemical Drugs

Author(s): Ryan Craig and Shulin Li

Volume 6, Issue 7, 2006

Page: [757 - 764] Pages: 8

DOI: 10.2174/138955706777698615

Price: $65

Abstract

Tumor-targeted chemo- or gene-therapies is a new form of treatment which provides the benefits ofreducing systemic toxicity, increasing the tolerance, and enhancing therapeutic efficacy. This review willdiscuss the discovery, function, application, and mechanism by which the short peptides (5-9) work for tumor-targeted gene or drug delivery.

Keywords: Peptide, tumor-targeting, tumor vessel, gene therapy, gene delivery, drug delivery, adhesion molecule, phage display


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