Characterization of Bovine Tau-Preparations by Two-Dimensional Gel Electrophoresis

Author(s): Daniela Volke, Ralf Hoffmann.

Journal Name: Protein & Peptide Letters

Volume 13 , Issue 6 , 2006

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Abstract:

The molecular diversity of bovine τ obtained by three different preparation protocols was characterized by immunoblot analyses after two-dimensional gel electrophoresis. These analyses revealed that t was heterogeneously modified, that is, up to 20 spots separated along the pH gradient, mostly independent of the preparation protocol.

Keywords: Alzheimer's disease, mass spectrometry, PHF-τ, phosphoprotein stain, phosphorylation, septin

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Article Details

VOLUME: 13
ISSUE: 6
Year: 2006
Page: [617 - 625]
Pages: 9
DOI: 10.2174/092986606777145805
Price: $58

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