Topical Imiquimod: Mechanism of Action and Clinical Applications

Author(s): David Vidal.

Journal Name: Mini-Reviews in Medicinal Chemistry

Volume 6 , Issue 5 , 2006

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Abstract:

Imiquimod is a synthetic imidazoquinoline heterocyclic amine of 240.3 Da (C14H16N4). Imiquimod is a cytokine inducer and a modifier of the innate immune response, as well as acquired antiviral and antitumor immune responses. Imiquimod 5% cream has proven to be an effective treatment for external genital warts, superficial basal cell carcinoma, and actinic keratosis.

Keywords: Imiquimod, imidazoquinolone, immune response modifier, toll-like receptor, skin infection, skin cancer

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Article Details

VOLUME: 6
ISSUE: 5
Year: 2006
Page: [499 - 503]
Pages: 5
DOI: 10.2174/138955706776876131
Price: $58

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