Synthesis and Biological Activity of New 4β-N-Heteroaryl Analogues of Podophyllotoxin
B. A. Kumar,
Sunanda G. Dastidar.
Some new 4β-N-heteroaryl analogues of podophyllotoxin have been prepared by employing Red Phosphorous/I2 reagent system. These 4β-N-heteroaryl analogues have been evaluated for their cytotoxicity against six human cancer cell lines and some representative ones have shown promising anticancer activity.
Keywords: Epipodophyllotoxin, benzothiazoles, pyrimidines, anticancer activity
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